3D Human Tissue Models for HIV Working Group. Electronic address: dwight.yin@nih.gov. 3D human tissue models and microphysiological systems for HIV and related comorbidities. Trends Biotechnol. 2023 Dec 8:S0167-7799(23)00299-8. doi: 10.1016/j.tibtech.2023.10.008. Epub ahead of print. PMID: 38071144.
Archives: Publications
Publications
Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states
Ndhlovu LC, Bendall ML, Dwaraka V, Pang AP, Dopkins N, Carreras N, Smith R, Nixon DF, Corley MJ. Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states. bioRxiv [Preprint]. 2023 Dec 7:2023.12.06.570422. doi: 10.1101/2023.12.06.570422. PMID: 38106164; PMCID: PMC10723416
Protocol for an in vitro assay to study HIV-1 Tat methylation
Boehm D, Kaehlcke K, Schnoelzer M, Ott M. Protocol for an in vitro assay to study HIV-1 Tat methylation. STAR Protoc. 2023 Nov 17;4(4):102687. doi: 10.1016/j.xpro.2023.102687. Epub ahead of print. PMID: 37979180; PMCID: PMC10694577.
HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing
Lyons, D.E.; Kumar, P.; Roan, N.R.; Defechereux, P.A.; Feschotte, C.; Lange, U.C.; Murthy, N.; Sameshima, P.; Verdin, E.; Ake, J.A.; Furler O’Brien, R.; et al. HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing. Viruses 2023, 15, 2171. https://doi.org/10.3390/v15112171
The latent HIV reservoir: current advances in genetic sequencing approaches
Preeti Moar, Thomas A. Premeaux, Andrew Atkins, Lishomwa C. Ndhlovu and Vinayaka R. Prasad
Identification of system-level features in HIV migration within a host
Goyal R, De Gruttola V, Gianella S, Caballero G, Porrachia M, Ignacio C, Woodworth B, Smith DM, Chaillon A. Identification of system-level features in HIV migration within a host. PLoS One. 2023 Sep 26;18(9):e0291367. doi: 10.1371/journal.pone.0291367. PMID: 37751407; PMCID: PMC10521982.
Exploiting a rodent cell block for intrinsic resistance to HIV-1 gene expression in human T cells
Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV
Corley MJ, Pang APS, Shikuma CM, Ndhlovu LC. Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV. Aging Cell. 2023 Sep 7:e13926. doi: 10.1111/acel.13926. Epub ahead of print. PMID: 37675817.
Comprehensive synergy mapping links a BAF- and NSL-containing “supercomplex” to the transcriptional silencing of HIV-1
Li Z, Deeks SG, Ott M, Greene WC. Comprehensive synergy mapping links a BAF- and NSL-containing “supercomplex” to the transcriptional silencing of HIV-1. Cell Rep. 2023 Sep 26;42(9):113055. doi: 10.1016/j.celrep.2023.113055. Epub 2023 Sep 7. PMID: 37682714; PMCID: PMC10591912.
Beyond the Syndemic of Opioid Use Disorders and HIV: The Impact of Opioids on Viral Reservoirs
Trunfio M, Chaillon A, Beliakova-Bethell N, Deiss R, Letendre SL, Riggs PK, Higgins N, Gianella S. Beyond the Syndemic of Opioid Use Disorders and HIV: The Impact of Opioids on Viral Reservoirs. Viruses. 2023 Aug 9;15(8):1712. doi: 10.3390/v15081712. PMID: 37632053; PMCID: PMC10458944.