Popovitz, Juliana; Sharma, Rohit; Hoshyar, Reyhane; Soo Kim, Beob; Murthy, Niren; Lee, Kunwoo Gene editing therapeutics based on mRNA delivery. Advanced drug delivery reviews2023 Sep; 200 115026
Archives: Publications
Publications
Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data
Chen, X., Wang, Y., Cappuccio, A. et al. Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data. Nat Comput Sci 3, 644–657 (2023). https://doi.org/10.1038/s43588-023-00476-5
Effect of Immune-Modulatory Interventions on Asymptomatic Cytomegalovirus Shedding During Suppressive Antiretroviral Therapy
Hastie E, Moser C, Sun X, Lennox J, Hsue PY, Bosch RJ, Deeks S, Meneses MV, Lederman MM, Hunt P, Henrich TJ, Marconi VC, Gianella S. Effect of Immune-Modulatory Interventions on Asymptomatic Cytomegalovirus Shedding During Suppressive Antiretroviral Therapy. J Infect Dis. 2023 Jun 28;228(1):64-69. doi: 10.1093/infdis/jiad060. PMID: 36881933; PMCID: PMC10490531
A Novel UHPLC-MS/MS Method for the Quantification of Seven Opioids in Different Human Tissues.
Manca A, De Nicolò A, De Vivo ED, Ferrara M, Oh S, Khalili S, Higgins N, Deiss RG, Bonora S, Cusato J, Palermiti A, Mula J, Gianella S, D’Avolio A. A Novel UHPLC-MS/MS Method for the Quantification of Seven Opioids in Different Human Tissues. Pharmaceuticals (Basel). 2023 Jun 19;16(6):903. doi: 10.3390/ph16060903. PMID: 37375850; PMCID: PMC10300969.
Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy
Tang Y, Chaillon A, Gianella S, Wong LM, Li D, Simermeyer TL, Porrachia M, Ignacio C, Woodworth B, Zhong D, Du J, de la Parra Polina E, Kirchherr J, Allard B, Clohosey ML, Moeser M, Sondgeroth AL, Whitehill GD, Singh V, Dashti A, Smith DM, Eron JJ, Bar KJ, Chahroudi A, Joseph SB, Archin NM, Margolis DM, Jiang G. Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy. J Clin Invest. 2023 Jun 15;133(12):e167417. doi: 10.1172/JCI167417. PMID: 37317962; PMCID: PMC10266791.
Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection
Ahuja SK, Manoharan MS, Lee GC, McKinnon LR, Meunier JA, Steri M, Harper N, Fiorillo E, Smith AM, Restrepo MI, Branum AP, Bottomley MJ, Orrù V, Jimenez F, Carrillo A, Pandranki L, Winter CA, Winter LA, Gaitan AA, Moreira AG, Walter EA, Silvestri G, King CL, Zheng YT, Zheng HY, Kimani J, Blake Ball T, Plummer FA, Fowke KR, Harden PN, Wood KJ, Ferris MT, Lund JM, Heise MT, Garrett N, Canady KR, Abdool Karim SS, Little SJ, Gianella S, Smith DM, Letendre S, Richman DD, Cucca F, Trinh H, Sanchez-Reilly S, Hecht JM, Cadena Zuluaga JA, Anzueto A, Pugh JA; South Texas Veterans Health Care System COVID-19 team; Agan BK, Root-Bernstein R, Clark RA, Okulicz JF, He W. Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection. Nat Commun. 2023 Jun 13;14(1):3286. doi: 10.1038/s41467-023-38238-6. PMID: 37311745; PMCID: PMC10264401.
Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication
Bajaj T, Wehri E, Suryawanshi RK, King E, Pardeshi KS, Behrouzi K, Khodabakhshi Z, Schulze-Gahmen U, Kumar GR, Mofrad MRK, Nomura DK, Ott M, Schaletzky J, Murthy N. Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication. RSC Adv. 2023 Jun 12;13(26):17667-17677. doi: 10.1039/d3ra01915b. PMID: 37312993; PMCID: PMC10259201.
A partner protection package for HIV cure-related trials involving analytical treatment interruptions
Karine Dubé DrPH, Tia Morton RN, Lawrence Fox MD, Lynda Dee JD, David Palm MS, Thomas J Villa, William Freshwater, Jeff Taylor, Gail Graham, William B Carter, John A Sauceda PhD, Michael J Peluso MD, Annette Rid MD
Perceived risks and benefits of enrolling people with HIV at the end of life in cure research in Southern California, United States
Dubé K, Shelton B, Patel H, Ndukwe SO, Concha-Garcia S, Dullano C, Solso S, Hendrickx S, Kaytes A, Taylor J, Villa TJ, Little SJ, Riggs PK, Lessard D, Arora AK, Costiniuk CT, Eskaf S, Smith DM, Gianella S. Perceived risks and benefits of enrolling people with HIV at the end of life in cure research in Southern California, United States. J Virus Erad. 2023 Jun 5;9(2):100328. doi: 10.1016/j.jve.2023.100328. PMID: 37440872; PMCID: PMC10334343.
A Community-Driven Framework to Prioritize the Use of Donated Human Biological Materials in the Context of HIV Cure-Related Research at the End of Life
Dubé K, Villa TJ, Taylor J, Kaytes A, Moore DJ, Little SJ, Chaillon A, Smith DM, Gianella S. A Community-Driven Framework to Prioritize the Use of Donated Human Biological Materials in the Context of HIV Cure-Related Research at the End of Life. Pathog Immun. 2023 May 24;8(1):1-16. doi: 10.20411/pai.v8i1.583. PMID: 37252012; PMCID: PMC10225111.