Tavora, R., Zhang, L., Tran, M. H., Li, H., O’Hagan, D., Pan, A., . . . Valente, S. T. (2025). Halting Recombinant Adeno-Associated Virus Transgene Expression Using mRNA-Lipid Nanoparticle-Delivered Meganucleases. Human Gene Therapy. doi:10.1089/hum.2025.011
Archives: Publications
Publications
Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors
Ma Y, Li C, Valente S. Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors. Epigenetics Chromatin. 2025 Apr 16;18(1):21. doi: 10.1186/s13072-025-00582-w. PMID: 40241225; PMCID: PMC12004603.
FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells
Gibaut QMR, Li C, Cheng A, Moranguinho I, Mori LP, Valente ST. FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells. Mol Ther Nucleic Acids. 2025 Mar 25;36(2):102525. doi: 10.1016/j.omtn.2025.102525. PMID: 40248217; PMCID: PMC12005928.
Stem cell transplantation and allogeneic immunity: post treatment control or HIV cure?
Cleary, Megana; Ndhlovu, Lishomwa C.b; Sacha, Jonah B.a,c. Stem cell transplantation and allogeneic immunity: post treatment control or HIV cure?. Current Opinion in HIV and AIDS ():10.1097/COH.0000000000000892, October 22, 2024. | DOI: 10.1097/COH.0000000000000892
Partner Protections in HIV Cure-Related Trials Involving Analytical Treatment Interruption: Updated Toolkit to Mitigate HIV Transmission Risk
Li, S., Nguyen, K., & Yang, H. (2024). The cancer-immune setpoint in HIV cure. Cell Reports Medicine, 5(8), 100923. https://doi.org/10.1016/j.xcrm.2024.100923
Silencing the transcriptionally active HIV reservoir to improve treatment outcomes
Prigann, J., Tavora, R., Furler O’Brien, R.L. et al. Silencing the transcriptionally active HIV reservoir to improve treatment outcomes. Nat Microbiol (2024). https://doi.org/10.1038/s41564-024-01816-5
Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements
Jang, Y., & Kim, Y. (2024). Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements. Aging Cell, 23(2), e14288. https://doi.org/10.1111/acel.14288
Transcriptional and methylation outcomes of didehydro-cortistatin A use in HIV-1–infected CD4+ T cells
Mori, L. P., Corley, M. J., McAuley, A. T., Pang, A., Venables, T., Ndhlovu, L. C., . . . Valente, S. T. (2024). Transcriptional and methylation outcomes of didehydro-cortistatin A use in HIV-1–infected CD4<sup>+</sup> T cells. Life Science Alliance, 7(10), e202402653. doi:10.26508/lsa.202402653
The single-cell opioid responses in the context of HIV (SCORCH) consortium
Ament, S.A., Campbell, R.R., Lobo, M.K. et al. The single-cell opioid responses in the context of HIV (SCORCH) consortium. Mol Psychiatry (2024). https://doi.org/10.1038/s41380-024-02620-7
People with HIV at the end-of-life and their next-of-kin/loved ones are willing to participate in interventional HIV cure-related research
Ndukwe SO, Patel H, Shelton B, Concha-Garcia S, Dullano C, Solso S, Hendrickx S, Riggs PK, Villa TJ, Kaytes A, Taylor J, Little SJ, Lessard D, Arora AK, Costiniuk CT, Eskaf S, Smith DM, Gianella S, Dubé K. People with HIV at the end-of-life and their next-of-kin/loved ones are willing to participate in interventional HIV cure-related research. AIDS. 2024 Feb 1;38(2):235-243. doi: 10.1097/QAD.0000000000003754. Epub 2023 Oct 17. PMID: 37861674.