Archives: Publications
Publications
Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV
Corley MJ, Pang APS, Shikuma CM, Ndhlovu LC. Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV. Aging Cell. 2023 Sep 7:e13926. doi: 10.1111/acel.13926. Epub ahead of print. PMID: 37675817.
HIV-1 transcriptional modulation: novel host factors and prospective therapeutic strategies
Gibaut QMR, Mori LP, Valente ST. HIV-1 transcriptional modulation: novel host factors and prospective therapeutic strategies. Curr Opin HIV AIDS. 2023 Sep 1;18(5):264-272. doi: 10.1097/COH.0000000000000808. Epub 2023 Jul 17. PMID: 37535041; PMCID: PMC10403276.
Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data
Chen, X., Wang, Y., Cappuccio, A. et al. Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data. Nat Comput Sci 3, 644–657 (2023). https://doi.org/10.1038/s43588-023-00476-5
A partner protection package for HIV cure-related trials involving analytical treatment interruptions
Karine Dubé DrPH, Tia Morton RN, Lawrence Fox MD, Lynda Dee JD, David Palm MS, Thomas J Villa, William Freshwater, Jeff Taylor, Gail Graham, William B Carter, John A Sauceda PhD, Michael J Peluso MD, Annette Rid MD
RNA Conformational Propensities Determine Cellular Activity
Ken, M.L., Roy, R., Geng, A. et al. RNA conformational propensities determine cellular activity. Nature 617, 835–841 (2023). https://doi.org/10.1038/s41586-023-06080-x
Confounding factors in profiling of locus-specific human endogenous retrovirus (HERV) transcript signatures in primary T cells using multi-study-derived datasets
Hamann, M.V., Adiba, M. & Lange, U.C. Confounding factors in profiling of locus-specific human endogenous retrovirus (HERV) transcript signatures in primary T cells using multi-study-derived datasets. BMC Med Genomics 16, 68 (2023). https://doi.org/10.1186/s12920-023-01486-y
The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11
Boehm D, Lam V, Schnolzer M, Ott M. The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11. Cell Rep. 2023 Mar 9;42(3):112234. doi: 10.1016/j.celrep.2023.112234. Epub ahead of print. PMID: 36897778.
The chaperone protein p32 stabilizes HIV-1 Tat and strengthens the p-TEFb/RNAPII/TAR complex promoting HIV transcription elongation
Chuan Li, Luisa P. Mori, Shuang Lyu, Ronald Bronson, Adam J. Getzler, Matthew E. Pipkin, and Susana T. Valente
Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice
Yuan Z, Giron LB, Hart C, Gyampoh A, Koshy J, Hong KY, Niki T, Premeaux TA, Ndhlovu LC, Deleage
C, Montaner LJ, Abdel-Mohsen M.