HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART Shelli F. Farhadian,1,2 Ofir Lindenbaum,3,4 Jun Zhao,4,5 Michael J. Corley,6,7 Yunju Im,8 Hannah Walsh,1 Alyssa Vecchio,9 Rolando Garcia-Milian,10 Jennifer Chiarella,2 Michelle Chintanaphol,2 Rachela Calvi,2 Guilin Wang,11 Lishomwa C. Ndhlovu,6,7 Jennifer Yoon,1 Diane Trotta,5 Shuangge Ma,8 Yuval Kluger,3,4,12 and Serena Spudich2