Mori, Luisa P., Li, C., Venables, T., McAuley, Andrew T., Getzler, Adam J., Wang, Q., . . . Valente, Susana T. (2025). The p400 complex promotes HIV-1 latency by suppressing viral transcription and altering the host cell state. Nucleic Acids Research, 53(15). doi:10.1093/nar/gkaf764
Archives: Publications
Publications
Virological and Immunological Outcomes of Combined Therapeutic Interventions and Dendritic Cell Therapy in People Living with HIV
Lishomwa C Ndhlovu, Leila B Giron, Juliana Galinskas, Thomas A Premeaux, Alina P S Pang, Danilo Dias, Marcela Vassao de Almeida Baptista, Iart Luca Shytaj, Juliana T Maricato, Paulo R A Ferreira, Gisele Gosuen, Michael J Corley, Courtney M Friday, Scott A Bowler, Ermelindo Della Libera, Maria Cecilia Sucupira, James R Hunter, Luis Mário Janini, Mauro Schechter, Andrea Savarino, Ricardo Sobhie Diaz, the SPARC Working Group , Virological and Immunological Outcomes of Combined Therapeutic Interventions and Dendritic Cell Therapy in People Living with HIV, The Journal of Infectious Diseases, 2025;, jiaf430, https://doi.org/10.1093/infdis/jiaf430
Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes
Hamann, M. V., Godbole, S., Adiba, M., Leddy, S. M., Navolić, J., Tabatabai, G., . . . Neumann, J. E. (2025). Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes. Acta Neuropathologica Communications, 13(1), 159. doi:10.1186/s40478-025-02078-w
Halting Recombinant Adeno-Associated Virus Transgene Expression Using mRNA-Lipid Nanoparticle-Delivered Meganucleases
Tavora, R., Zhang, L., Tran, M. H., Li, H., O’Hagan, D., Pan, A., . . . Valente, S. T. (2025). Halting Recombinant Adeno-Associated Virus Transgene Expression Using mRNA-Lipid Nanoparticle-Delivered Meganucleases. Human Gene Therapy. doi:10.1089/hum.2025.011
Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors
Ma Y, Li C, Valente S. Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors. Epigenetics Chromatin. 2025 Apr 16;18(1):21. doi: 10.1186/s13072-025-00582-w. PMID: 40241225; PMCID: PMC12004603.
FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells
Gibaut QMR, Li C, Cheng A, Moranguinho I, Mori LP, Valente ST. FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells. Mol Ther Nucleic Acids. 2025 Mar 25;36(2):102525. doi: 10.1016/j.omtn.2025.102525. PMID: 40248217; PMCID: PMC12005928.
Stem cell transplantation and allogeneic immunity: post treatment control or HIV cure?
Cleary, Megana; Ndhlovu, Lishomwa C.b; Sacha, Jonah B.a,c. Stem cell transplantation and allogeneic immunity: post treatment control or HIV cure?. Current Opinion in HIV and AIDS ():10.1097/COH.0000000000000892, October 22, 2024. | DOI: 10.1097/COH.0000000000000892
Partner Protections in HIV Cure-Related Trials Involving Analytical Treatment Interruption: Updated Toolkit to Mitigate HIV Transmission Risk
Li, S., Nguyen, K., & Yang, H. (2024). The cancer-immune setpoint in HIV cure. Cell Reports Medicine, 5(8), 100923. https://doi.org/10.1016/j.xcrm.2024.100923
Silencing the transcriptionally active HIV reservoir to improve treatment outcomes
Prigann, J., Tavora, R., Furler O’Brien, R.L. et al. Silencing the transcriptionally active HIV reservoir to improve treatment outcomes. Nat Microbiol (2024). https://doi.org/10.1038/s41564-024-01816-5
Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements
Jang, Y., & Kim, Y. (2024). Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements. Aging Cell, 23(2), e14288. https://doi.org/10.1111/acel.14288