Mori, Luisa P., Li, C., Venables, T., McAuley, Andrew T., Getzler, Adam J., Wang, Q., . . . Valente, Susana T. (2025). The p400 complex promotes HIV-1 latency by suppressing viral transcription and altering the host cell state. Nucleic Acids Research, 53(15). doi:10.1093/nar/gkaf764
Publication Category: HIV/AIDS
Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes
Hamann, M. V., Godbole, S., Adiba, M., Leddy, S. M., Navolić, J., Tabatabai, G., . . . Neumann, J. E. (2025). Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes. Acta Neuropathologica Communications, 13(1), 159. doi:10.1186/s40478-025-02078-w
Halting Recombinant Adeno-Associated Virus Transgene Expression Using mRNA-Lipid Nanoparticle-Delivered Meganucleases
Tavora, R., Zhang, L., Tran, M. H., Li, H., O’Hagan, D., Pan, A., . . . Valente, S. T. (2025). Halting Recombinant Adeno-Associated Virus Transgene Expression Using mRNA-Lipid Nanoparticle-Delivered Meganucleases. Human Gene Therapy. doi:10.1089/hum.2025.011
Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors
Ma Y, Li C, Valente S. Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors. Epigenetics Chromatin. 2025 Apr 16;18(1):21. doi: 10.1186/s13072-025-00582-w. PMID: 40241225; PMCID: PMC12004603.
Stem cell transplantation and allogeneic immunity: post treatment control or HIV cure?
Cleary, Megana; Ndhlovu, Lishomwa C.b; Sacha, Jonah B.a,c. Stem cell transplantation and allogeneic immunity: post treatment control or HIV cure?. Current Opinion in HIV and AIDS ():10.1097/COH.0000000000000892, October 22, 2024. | DOI: 10.1097/COH.0000000000000892
Silencing the transcriptionally active HIV reservoir to improve treatment outcomes
Prigann, J., Tavora, R., Furler O’Brien, R.L. et al. Silencing the transcriptionally active HIV reservoir to improve treatment outcomes. Nat Microbiol (2024). https://doi.org/10.1038/s41564-024-01816-5
Transcriptional and methylation outcomes of didehydro-cortistatin A use in HIV-1–infected CD4+ T cells
Mori, L. P., Corley, M. J., McAuley, A. T., Pang, A., Venables, T., Ndhlovu, L. C., . . . Valente, S. T. (2024). Transcriptional and methylation outcomes of didehydro-cortistatin A use in HIV-1–infected CD4<sup>+</sup> T cells. Life Science Alliance, 7(10), e202402653. doi:10.26508/lsa.202402653
The single-cell opioid responses in the context of HIV (SCORCH) consortium
Ament, S.A., Campbell, R.R., Lobo, M.K. et al. The single-cell opioid responses in the context of HIV (SCORCH) consortium. Mol Psychiatry (2024). https://doi.org/10.1038/s41380-024-02620-7
A single-cell transposable element atlas of human cell identity
3D human tissue models and microphysiological systems for HIV and related comorbidities
3D Human Tissue Models for HIV Working Group. Electronic address: dwight.yin@nih.gov. 3D human tissue models and microphysiological systems for HIV and related comorbidities. Trends Biotechnol. 2023 Dec 8:S0167-7799(23)00299-8. doi: 10.1016/j.tibtech.2023.10.008. Epub ahead of print. PMID: 38071144.